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Cymbalta is an antidepressant. It is used to treat depression. It is also used to treat pain caused by complications of diabetes or pain caused by fibromyalgia.
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She's referring to Cymbalta, an established antidepressant that is over the counter alternative to cymbalta approved to treat depression and bipolar disorder but has been accused of causing increased risk suicide and aggression.
According to the Department of Health and Human Services' Center for Drug Evaluation and Research, the has "been associated with an increased risk of suicide, suicidal ideation, and behaviors in children, adolescents, young adults, as well in adults who had previously been hospitalized for depression."
The Drug Enforcement Administration also issued a warning earlier this year, that patients should not turn to Cymbalta as their primary treatment for depression, and that prescribing the drug will be considered abuse or diversion.
The drug is also known to have "an increased risk of hypoglycemia". The FDA also warned that patients who experience symptoms of hypoglycemia while on Cymbalta should not stop taking the drug without consulting with their doctor. That said, no serious cases of hypoglycemia have been reported while taking Cymbalta.
To avoid potential side effects, Dr. Paul Knoepfler, M.D., a consultant psychiatrist at the Columbia Presbyterian Medical Center in New York, recommends patients consult with their personal physician prior to starting treatment.
"The first thing patients should ask themselves is, 'What is the true diagnosis?', as opposed to, 'Has my doctor recommended something, should I take it?'" says Knoepfler.
As to why the FDA gave drug a black eye, Knoepfler believes its recent popularity may have something to do with increased media attention. "It's as if the marketing took
cymbalta from canada price a nosedive and the FDA made a mistake," he said. "I think it's a public relations issue."
Knoepfler, who was previously the lead clinical researcher on FDA's suicide drugs advisory committee — a group of 20 or so doctors, including many practicing psychiatrists — also believes people need to understand that Cymbalta is not a "first line" drug.
"We use medications to treat the depression, and we mood swings to help the patient be functional," says Knoepfler. "I think more people need to be educated on that because a lot of people believe that if they take Cymbalta are going to become completely depressed, whereas it's not going to be the case like that."
Knoepfler recommends that women who plan to start taking the drug call their personal physician and make sure they know what the drug can and cannot do for them. Women also need to ask their doctor about the potential risk of blood clots.
"If the patient really needs to be taking it, I tell them to try it," he adds.
Although Cymbalta is not approved for women, Knoepfler recommends that they speak with their physician before taking it. He also cautions that women who are planning to take it at any time need to have an emergency physician's consultation before stopping.
In addition to this safety concern, there are
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Cymbalta is typically dispensed in a 30-day supply. The drug is only to be taken as needed, and is a powerful psychiatric option, but not for everyone, says Knoepfler.
"If patients want to take this, they should go talk to a patient advocate. They are there to help them and they are there to help them get the treatment that makes sense."
Additional reporting by Laura MacMillan.
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